The reason that you see anything on a PET scan is because the DG in FDG gets into any cell that sucks up sugar, and can't get out of the cell because it is launched down an enzymatic pathway and becomes DG-6-P.
The 18-F that is bound to this then gives off signals.
So, the things that light up are things that use sugar:
- brain
- heart
- strap muscles and salivary glands.
- tongue muscles if the patient is talking
- anything which is very cellular, such as infection and malignancy.
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